The Human Plasma Proteome
نویسندگان
چکیده
منابع مشابه
The Human Plasma Proteome
The human plasma proteome holds the promise of a revolution in disease diagnosis and therapeutic monitoring provided that major challenges in proteomics and related disciplines can be addressed. Plasma is not only the primary clinical specimen but also represents the largest and deepest version of the human proteome present in any sample: in addition to the classical “plasma proteins,” it conta...
متن کاملExploring the human plasma proteome.
The Human Proteome Organization (HUPO) has launched several major initiatives to explore the proteomes of liver, brain, and plasma and to generate informatics standards and large-scale antibody production. This issue of PROTEOMICS presents 28 papers from the pilot phase of the Human Plasma Proteome Project. The papers represent a combination of collaborative analyses of HUPO PPP reference speci...
متن کاملTHE HUPO Human Plasma Proteome Project.
The Human Proteomics Organization (HUPO) Human Plasma Proteome Project (PPP) is a prominent example of the inherently collaborative nature of the overall community effort to characterize the proteome of humans in health and disease. The PPP Pilot Phase, called "Exploring the Human Plasma Proteome", engaged 55 laboratories, four technical committees, and vendors and sponsors on an international ...
متن کاملMapping the human plasma proteome by SCX-LC-IMS-MS.
The advent of on-line multidimensional liquid chromatography-mass spectrometry has significantly impacted proteomic analyses of complex biological fluids such as plasma. However, there is general agreement that additional advances to enhance the peak capacity of such platforms are required to enhance the accuracy and coverage of proteome maps of such fluids. Here, we describe the combination of...
متن کاملIdentification of genetic variants influencing the human plasma proteome.
Genetic variants influencing the transcriptome have been extensively studied. However, the impact of the genetic factors on the human proteome is largely unexplored, mainly due to lack of suitable high-throughput methods. Here we present unique and comprehensive identification of genetic variants affecting the human plasma protein profile by combining high-throughput and high-resolution mass sp...
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ژورنال
عنوان ژورنال: Molecular & Cellular Proteomics
سال: 2002
ISSN: 1535-9476
DOI: 10.1074/mcp.r200007-mcp200